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thyA [2019-07-02 10:00:52]
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thyA [2019-07-02 10:00:52]

thymidylate synthase A
Locus
BSU17680
Isoelectric point
5.50
Molecular weight
32.65 kDa
Protein length
279 aa Sequence Blast
Gene length
840 bp Sequence Blast
Function
biosynthesis of thymidine nucleotides
Product
thymidylate synthase A
Essential
no
E.C.
2.1.1.45
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,902,219 1,903,058

The protein

Catalyzed reaction/ biological activity

  • 5,10-methylenetetrahydrofolate dUMP = dihydrofolate dTMP (according to Swiss-Prot)
  • Protein family

  • thymidylate synthase family (with ThyB, according to UniProt)
  • Paralogous protein(s)

    Structure

    Localization

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    Biological materials

    Mutant

  • BKE17680 (thyA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGACTATTCATATCCTTC, downstream forward: _UP4_TAATGCTGCCTTTTTATTGT
  • BKK17680 (thyA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGACTATTCATATCCTTC, downstream forward: _UP4_TAATGCTGCCTTTTTATTGT
  • References

    Reviews

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    Original publications

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